فرنوش جعفرپور

استادیار گروه زیست شناسی

گروه آموزشی : زیست شناسی
شماره تماس : 95015696 - 31 - (98+)
نحوه همکاری : همکار پژوهشکده رویان
سمت : پژوهشگر (پژوهشگاه رویان)
رایانامه : Jafarpour.Farnoosh[at]Gmail.Com

  • دکترای تخصصی، آناتومی و جنین شناسی، دانشکده دامپزشکی –دانشگاه شیراز، 1389-1384 .
  • دکترای حرفه ای، دکترای عمومی دامپزشکی، دانشکده دامپزشکی –دانشگاه شیراز، 1383-1377 .
  • ژنتیک سرطان
  • بافت شناسی
  • جنین شناسی
  • سلوبهای بنیادی
  • بیوتکنولوژی
  • ژنتیک سرطان
  • 1-Comparative dynamics of 5-methylcytosine reprogramming and TET family expression during preimplantation mammalian development in mouse and sheep. Jafarpour F, Hosseini SM, Ostadhosseini S, Abbasi H, Dalman A, Nasr-Esfahani MH. Theriogenology. 2017 Feb;89:86-96. doi: 10.1016/j.theriogenology.2016.10.010.
  • 2-Vitrification at Day3 stage appears not to affect the methylation status of H19/IGF2 differentially methylated region of in vitro produced human blastocysts. Derakhshan-Horeh M, Abolhassani F, Jafarpour F, Moini A, Karbalaie K, Hosseini SM, Nasr-Esfahani MH. Cryobiology. 2016 Oct;73(2):168-74. doi: 10.1016/j.cryobiol.2016.08.003.
  • 3-Methylation Status of H19/IGF2 Differentially Methylated Region in in vitro Human Blastocysts Donated by Healthy Couples. Derakhshan-Horeh M, Abolhassani F, Jafarpour F, Moini A, Karbalaie Kh, Hosseini SM, Ostadhosseini S, Nasr-Esfahani MH. Iran Biomed J. 2017 Jan;21(1):16-23.
  • 4-Epigenetic modification with trichostatin A does not correct specific errors of somatic cell nuclear transfer at the transcriptomic level; highlighting the non-random nature of oocyte-mediated reprogramming errors. Hosseini SM, Dufort I, Nieminen J, Moulavi F, Ghanaei HR, Hajian M, Jafarpour F, Forouzanfar M, Gourbai H, Shahverdi AH, Nasr-Esfahani MH, Sirard MA. BMC Genomics. 2016 Jan 4;17:16. doi: 10.1186/s12864-015-2264-z.
  • 5-Contrasting effects of G1.2/G2.2 and SOF1/SOF2 embryo culture media on pre- and post-implantation development of non-transgenic and transgenic cloned goat embryos. Hosseini SM, Hajian M, Ostadhosseini S, Forouzanfar M, Abedi P, Jafarpour F, Gourabi H, Shahverdi AH, Vosough A, Ghanaie HR, Nasr-Esfahani MH. Reprod Biomed Online. 2015 Sep;31(3):372-83. doi: 10.1016/j.rbmo.2015.06.008.
  • 6-A physiological, rather than a superovulated, post-implantation environment can attenuate the compromising effect of assisted reproductive techniques on gene expression in developing mice embryos. Bonakdar E, Edriss MA, Bakhtari A, Jafarpour F, Asgari V, Hosseini SM, Boroujeni NS, Hajian M, Rahmani HR, Nasr-Esfahani MH. Mol Reprod Dev. 2015 Mar;82(3):191-206. doi: 10.1002/mrd.22461.
  • 7-Effect of epigenetic modification with trichostatin A and S-adenosylhomocysteine on developmental competence and POU5F1-EGFP expression of interspecies cloned embryos in dog. Mousai M, Hosseini SM, Hajian M, Jafarpour F, Asgari V, Forouzanfar M, Nasr-Esfahani MH. Zygote. 2015 Oct;23(5):758-70. doi: 10.1017/S0967199414000410.
  • 8-The interfering effects of superovulation and vitrification upon some important epigenetic biomarkers in mouse blastocyst. Bakhtari A, Rahmani HR, Bonakdar E, Jafarpour F, Asgari V, Hosseini SM, Hajian M, Edriss MA, Nasr-Esfahani MH. Cryobiology. 2014 Dec;69(3):419-27. doi: 10.1016/j.cryobiol.2014.09.379.
  • 9-Enucleated ovine oocyte supports human somatic cells reprogramming back to the embryonic stage. Hosseini SM, Hajian M, Forouzanfar M, Moulavi F, Abedi P, Asgari V, Tanhaei S, Abbasi H, Jafarpour F, Ostadhosseini S, Karamali F, Karbaliaie K, Baharvand H, Nasr-Esfahani MH. Cell Reprogram. 2012 Apr;14(2):155-63. doi: 10.1089/cell.2011.0061.
  • 10-Epigenetic modification does not determine the time of POU5F1 transcription activation in cloned bovine embryos. Jafari S, Hosseini SM, Hajian M, Forouzanfar M, Jafarpour F, Abedi P, Ostadhosseini S, Abbasi H, Gourabi H, Shahverdi AH, Vosough AD, Anjomshoaa M, Haron AW, Nordin N, Yaakub H, Nasr-Esfahani MH. J Assist Reprod Genet. 2011 Nov;28(11):1119-27. doi: 10.1007/s10815-011-9638-1.
  • 11-Somatic cell-induced hyperacetylation, but not hypomethylation, positively and reversibly affects the efficiency of in vitro cloned blastocyst production in cattle. Jafarpour F, Hosseini SM, Hajian M, Forouzanfar M, Ostadhosseini S, Abedi P, Gholami S, Ghaedi K, Gourabi H, Shahverdi AH, Vosough AD, Nasr-Esfahani MH. Cell Reprogram. 2011 Dec;13(6):483-93. doi: 10.1089/cell.2011.0005.
  • 12-Developmental Competence and Pluripotency Gene Expression of Cattle Cloned Embryos Derived from Donor Cells Treated with 5-aza-2′-deoxycytidine. Jafarpour F, Hosseini SM, Hajian M, Forouzanfar M, Abedi P, Hosseini L, Ostadhosseini S, Gholami S, Nasr Esfahani MH. Int J Fertil Steril. 2011 Jan;4(4):148-55
  • 13-Identification of a Specific Pseudo attP Site for Phage PhiC31 Integrase in Bovine Genome. Mohammad Hadi Sekhavati; Mojtaba Tahmoorespur; Farnoosh Jafarpour; Kianoush Dormiani; Yahya Khazaie; Kamran Ghaedi; Sayyed Morteza Hosseini; Mahboobeh Forouzanfar; Mohammad Hossein Nasr Esfahani. Iranian Journal of Biotechnology 2014 12:1-9.
  • 14-Improved in vitro development of cloned bovine embryos using S-adenosylhomocysteine, a non-toxic epigenetic modifying reagent. Jafari S1, Hosseini MS, Hajian M, Forouzanfar M, Jafarpour F, Abedi P, Ostadhosseini S, Abbasi H, Gourabi H, Shahverdi AH, Dizaj AV, Anjomshoaa M, Haron W, Noorshariza N, Yakub H, Nasr-Esfahani MH. Mol Reprod Dev. 2011 Aug;78(8):576-84. doi: 10.1002/mrd.21344. Epub 2011 Jun 30.
  • 15- Effect of GnRH on guinea pig endometrium at preimplantation stage. Jelodar GA1, Gholami S, Jafarpour F. Indian J Exp Biol. 2007 Mar;45(3):242-6.
  • 16- مقايسه­ي تأثير دو نوع محيط کشت دست­ساز و (SOF) و تجاری (G1/G2) بر تکوين آزمايشگاهي جنین­های منجمد و غير منجمد موشي الهام بنکدار، محمدعلی ادریس، عزیزالله باختري، فرنوش جعفرپور، وجيهه عسگری، سيد مرتضي حسيني، مهدي حاجيان، محمدحسين نصر اصفهانی نشریه علوم درمانگاهی دامپزشکی ایران آبان 1393.
  1. The role of Epigenetic Modifiers on In Vitro Development of Buffalo-Bovine Interspe­cies Cloned Embryo, 17th Royan International Twin Congress, Royan Institute.
  2. Methylation level of H19/IGF2 differentially methylated region (DMR) in human blastocysts donated by fertile couple, 32nd Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE), ESHREs.
  3. Improved efficiency of somatic cell nuclear transfer in sheep by persecution of recipient oocytes by brilliant cresyl blue staining, 1st International congress on reproduction (ISERB).
  4. Distinct epigenetic status of fully grown and growing oocytes selected by BCB staining, 1st International congress on reproduction (ISERB), پژوهشگاه ابن سینا.
  5. تغییرات پویای اپی­ژنتیک در طی اسپرماتوژنز و مراحل اولیه پس از لقاح، اولین سمپوزیوم بیولوژی اسپرم، 05 آذر 1394، Royan Institute.
  6. Dynamic reprogramming of 5-methylcytosine, 5-hydroxymethylcytosine and 5-carboxylcytosine during early ovine development, 1st International congress on reproduction (ISERB), پژوهشگاه ابن سینا.
  7. A Preliminary Report on Production of Organ Deficient Goats at Royan Institute of Biotechnology, 15th Royan International Twin Congress. Royan Institute.
  8. Improved Efficiency of Somatic Cell Nuclear Transfer in Sheep by Persecution of Recipient Oocytes with Brilliant Cresyl Blue Staining, 15th Royan International Twin Congress, Royan Institute.
  9. Aberrant Gene Expression Profile in Blastocyst Embryos As Consequences of Assisted Reproductive Technologies, 14th Royan International Twin Congress, Royan Institute.
  10. Distinct Epigenetic Status of Fully Grown and Growing Oocytes Selected by BCB Staining, 14th Royan International Twin Congress, Royan Institute.
  11. Comparison of the efficacy of two culture media (handmade vs. Commercial) on in vitro development of vitrified and non-vitrified mouse embryos, 14th Royan International Twin Congress, Royan Institute.
  12. Effect of Mouse Embryo Vitrification on Histone Modifications, 13th Royan International Twin Congress, Royan Institute.
  13. Mouse embryo vitrification cannot effect on global DNA methylation in preimplantation stage, 13th Royan International Twin Congress, Royan Institute.
  14. Epigenetic Modification of Cloned Embryo Development; State of ART, 12th Royan International Twin Congress, Royan Institute.